At what temperature does tissue damage begin?

Tissue damage begins around 45 degrees Celsius, which is significant because at this temperature, proteins start to denature, and cellular structures can become compromised. This leads to cell injury or death, as the body's normal physiological processes are disrupted.

Heat can cause burns and other forms of injury depending on exposure time, but at 45 degrees Celsius, the risk of thermal injury becomes considerably heightened. This understanding is crucial in medical and emergency contexts, as it informs treatment protocols for heat exposure or burns.

Higher temperatures beyond this threshold carry even greater risks for tissue damage; however, the onset of noticeable and detrimental effects starts around 45 degrees Celsius, establishing it as the critical point for assessing and responding to thermal injury.