What ratio was used for subject allocation in the ACCURATE study?

The correct answer indicates that a 1:1 ratio was used for subject allocation in the ACCURATE study. In clinical trials, a 1:1 ratio means that participants were evenly divided between the treatment and control groups. This balanced approach helps ensure that the results are not biased by differences in group sizes, thereby allowing for a more straightforward interpretation of the outcomes.

In a study using a 1:1 ratio, each participant has an equal chance of receiving either of the interventions, which can enhance the reliability and validity of the findings. This method is particularly useful for comparing the effectiveness and safety of two treatments, as any variations in results can be more confidently attributed to the treatment itself rather than to disproportionate group sizes.